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Double Marker Test: A Key Prenatal Screening for C
Double Marker Test: A Key Prenatal Screening for C
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Redcliffe Labs
4 posts
Apr 17, 2025
10:14 PM
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The Double Marker Test is a non-invasive prenatal screening conducted during the first trimester of pregnancy, usually between the 9th and 13th week. It measures two critical substances in the mother's blood — Free Beta hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein A). These markers help evaluate the risk of chromosomal abnormalities in the fetus, particularly Down syndrome (Trisomy 21), Trisomy 18, and other genetic conditions.
The test is typically recommended for women over 35, those with a family history of genetic disorders, or those who had abnormal ultrasound findings. While it does not provide a definitive diagnosis, the Double Marker Test, when combined with a nuchal translucency (NT) scan, gives a more accurate risk assessment. Based on the results, doctors may advise further testing like the Triple Marker Test, Non-Invasive Prenatal Testing (NIPT), or amniocentesis for confirmation.
This screening plays a crucial role in early risk detection, enabling informed decisions and timely medical interventions during pregnancy.
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